Disruption of Hepatic Leptin Signaling Protects Mice from Age- and Diet- Related Glucose Intolerance Running Title: Liver Leptin Signaling and Glucose Tolerance
نویسندگان
چکیده
1 Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada 2 Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom 3 Departments of Medicine and Neuroscience, Albert Einstein College of Medicine, New York, New York, U.S.A 4 Current Affiliation: Department of Biochemistry and Molecular Biology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada 5 Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada.
منابع مشابه
Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance
OBJECTIVE The liver plays a critical role in integrating and controlling glucose metabolism. Thus, it is important that the liver receive and react to signals from other tissues regarding the nutrient status of the body. Leptin, which is produced and secreted from adipose tissue, is a hormone that relays information regarding the status of adipose depots to other parts of the body. Leptin has a...
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